Lead generation and lead optimization, Structure Activity Relationships (SAR) and Structure Property Relationships (SPR), Fragment based and structure based hit expansion and evolutions. Parallel library synthesis (solution & solid phase).
Route scouting, synthetic methodology development, building blocks/scaffold synthesis, scale-up, non GMP API synthesis, nucleosides, nucleotides, peptides, peptide nucleic acid (PNA), un-natural amino acids and carbohydrate synthesis.
Design and synthesis of linkers, Antibody Drug Conjugates (ADC), Antibody-CDN conjugates, Antibody-oligonucleotide conjugates, protein small molecule conjugates, peptide nucleic acid conjugates, polysaccharide and lipid surface modification and conjugation.
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