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Services – CreaGen BioSciences Inc.
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Our scientists have significant expertise in all phases of medicinal chemistry, from intelligent molecule design to development of late-stage optimal molecular entities (OMEs) and preclinical candidates. Our experience ranges from idea generation and route scouting to synthetic route development and library synthesis. Whether the challenge requires re-synthesis of a competitor compound or a late stage lead optimization, we have the best experience and resources to meet or exceed customer expectations.



Our discovery research services include:



MEDICINAL CHEMISTRY

Exploratory chemistry, hit validation and evaluation, lead generation, lead optimization, structure-based drug design (SBDD), focused libraries.



SYNTHETIC CHEMISTRY

Parallel synthesis (solution and solid phase), building-blocks/scaffold synthesis, sample scale-up, intermediates and specialty chemicals, competitor sample preparation, heterocyclic chemistry, substituted boronic acids, solid phase peptide synthesis (up to gram scale), nucleotide synthesis.


BIOCONJUGATION CHEMISTRY

NMR spectroscopy, (1H, 13C, 19F, and 31P NMR spectroscopy), mass spectroscopy, HPLC analysis (MS, MSMS, ELSD, UV), chiral HPLC analysis/separations.


Our business model is flexible, and can be tailored to customer needs. We work either on a strict fee-for-service basis, or as part of a broader discovery collaboration to provide cost-effective services on an FTE basis. Our clients range from virtual and start-up companies to mid-size companies to multinational pharmaceutical companies. Since 2003, CreaGen has established a track record of excellence with satisfied customers ranging from multinational pharmaceutical companies to early-stage biotechnology start-up companies. CreaGen is poised for growth and we welcome the opportunity to help your organization to accomplish its most challenging research objectives.


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