Corporate Info

CreaGen Inc. operates a cutting-edge 22,000 sq ft research facility situated in Woburn, MA, a key center for life sciences just a short 15-minute drive from Cambridge. Our advanced lab houses 15 chemical and 5 bio-safety hoods, along with state-of-the-art automated systems for parallel synthesis and mass-directed auto purification. These systems facilitate High Throughput Synthesis (HTS) and High Throughput Purification (HTP), accelerating the creation of small molecule libraries. With a 20-year track record in medicinal chemistry and drug discovery, our scientific team has broad expertise in both synthetic and medicinal chemistry. The laboratory is fully equipped to perform a wide range of activities including organic synthesis, medicinal chemistry, lead optimization, biology, and cell culture experiments. This encompasses lead generation and optimization, structure-based drug design, and the complex synthesis of molecules such as nucleosides, nucleotides, and peptides. Our automated lab features high-throughput capabilities and analytical instruments like LCMS, mass-directed purification systems, and NMR, as well as a biochemistry lab outfitted for cell culture—making all these resources immediately available for the project at hand. Our seasoned team has demonstrated success in the field of oncology.

The biology lab contains instrumentation such as

a) Inverted microscope with phase contrast, brightfield, and digital imaging capabilities
b) Flow cytometer and automated cell counter
c) Real-time PCR system
d) Microplate fluorometer and luminometer
e) iBright FL1000 Imaging System for protein, nucleic acid, chemiluminescent, and fluorescent blots
f) Electrophoresis and Western blot equipment
g) Luminex MAGPIX® compact fluorescent detection system suitable for multiplex immunoassays
h) MACS cell separation equipment
i) Humidified cell culture incubators
j) Biological safety cabinet/laminar flow hood